A Comparison of the Efficacy and Safety of Balsalazide (Basazyde
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چکیده
causes inflammation and sores in the lining of the large intestine. The inflammation usually occurs in the rectum and lower part of the colon, but it may affect the entire colon. Most patients are treated with medications. Aminosalicylates were the first drug shown to be benefical in UC and the first widely used aminosalicylate was salfasalazine. Balsalazide is the first new oral medication in more than ten years that is designed to treat mild to moderate
منابع مشابه
Low dose balsalazide (1.5 g twice daily) and mesalazine (0.5 g three times daily) maintained remission of ulcerative colitis but high dose balsalazide (3.0 g twice daily) was superior in preventing relapses.
BACKGROUND Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug. Its efficacy in comparison with standard mesalazine therapy and the optimum dose for maintaining remission of ulcerative colitis are still unclear. AIMS To compare the relapse preventing effect and safety profile of two doses of balsalazide and a standard dose of Eudragit coated mesalazine. METHODS A total of ...
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تاریخ انتشار 2006